Antibiotics have become a central part of pediatric care, helping to reduce serious illness and save lives. However, through my review of current research, I found that using antibiotics in children is not always straightforward. When used inappropriately, these medications can cause unwanted side effects such as disruption of gut microbiota, immune system problems, and contribute to the growing issue of antibiotic resistance. This paper explores how antibiotics affect different organ systems in children, highlights the most commonly used antibiotic types, and discusses how we can use these medicines more safely and responsibly to protect child health.

Antibiotics, child health, microbiota disruption

Ventola, C. L. (2015). The antibiotic resistance crisis. Pharmacy and Therapeutics, 40(4), 277–283.

Blaser, M. J. (2016). Missing microbes: How the overuse of antibiotics is fueling our modern plagues. Macmillan.

WHO. (2022). Global action plan on antimicrobial resistance.

CDC. (2023). Antibiotic Use in Children: Recommendations and Reports.

Russell, S. L., et al. (2012). Early-life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma. EMBO Reports, 13(5), 440–447.

Korpela, K., et al. (2020). Childhood antibiotic use and weight gain: systematic review. Nature Reviews Endocrinology, 16(6), 317–325.

UNICEF. (2021). Guidelines on Rational Use of Medicines in Children.